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PE-22-28 is a synthetic derivative of the natural peptide spadin, specifically designed to bind with TREK-1 channels. TREK-1 is a potassium channel found in brain regions responsible for mood regulation, memory, and learning. This peptide is being investigated for its potential in areas such as antidepressant activity, stroke recovery, and neurodegenerative diseases like Alzheimer’s.

Key Benefits:

Antidepressant Activity: PE-22-28 may provide rapid relief from depressive symptoms, with noticeable effects typically seen within just four days. Unlike traditional antidepressants, which can take weeks to show results, PE-22-28 acts quickly. Additionally, it does not lead to dependency or withdrawal symptoms when discontinued, making it a safer alternative to conventional antidepressants.

Stroke Recovery: The peptide shows promise in supporting recovery from strokes by aiding neural repair and function.

Neurodegenerative Diseases: Research suggests that PE-22-28 may be beneficial in treating neurodegenerative conditions such as Alzheimer’s disease by affecting mood, memory, and cognitive functions.

TREK-1 Inhibition: As a TREK-1 inhibitor, PE-22-28 helps modulate the activity of this potassium channel, which is crucial for regulating mood and cognitive functions.

Cognitive Enhancement: PE-22-28 supports improvements in mood, memory, and learning, potentially enhancing cognitive performance and mental clarity.

Muscle Function: Preliminary data indicates that PE-22-28 may assist with muscle function, which could be beneficial for overall physical health and rehabilitation.

Clinical Insights:

While PE-22-28 has not yet been extensively studied in human subjects, preliminary research shows promising results. It is noted for its rapid action, providing significant antidepressant effects within four days, and lacking the withdrawal symptoms commonly associated with traditional antidepressants. As research progresses, PE-22-28 represents a potentially innovative approach to mental health treatment and neurological recovery, offering new possibilities for addressing depression and related conditions.

 

Molecular formula:

C35H55N11O9

Molecular weight:

773.9 g/mol

Purity:

99%+

Research Applications:

  • Treatment of Depression
  • Stimulating Neurogenesis and Synaptogenesis
  • Stroke Recovery
  • Memory and Learning
  • Muscle Function


Product Use: THIS PRODUCT IS STRICTLY FOR SCIENTIFIC RESEARCH PURPOSES ONLY. It should only be used in laboratory settings. All product information on this website is provided solely for educational purposes. The law strictly prohibits introducing this product into the body of humans or animals. Only licensed professionals should handle this product. This product is not a drug, food, or cosmetic and should not be improperly classified or used as such.

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