LL-37 2mg

LL-37 is a cathelicidin family antimicrobial peptide known for its potent broad-spectrum antimicrobial properties and role in immune defense mechanisms. It is naturally produced in the body and has emerged as a natural alternative to antibiotics due to its effectiveness against antibiotic-resistant infections.

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Molecular Characteristics

 • Molecular Formula: C205H340N60O53

 • Molecular Weight: 4493 g/mol

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Key Functions and Applications

 1. Antimicrobial Activity: LL-37 combats a wide range of pathogens including bacteria, viruses, and fungi. It is particularly effective against both Gram-negative and Gram-positive bacteria, including drug-resistant strains.

 2. Anti-Biofilm Properties: The peptide disrupts biofilm formation by pathogens such as Staphylococcus aureus and Candida albicans, making it valuable in treating persistent infections.

 3. Wound Healing: LL-37 enhances wound repair by stimulating blood vessel formation, skin regeneration, and accelerating wound closure.

 4. Immunomodulation: It regulates immune responses, enhancing neutrophil survival, reducing inflammatory cytokines, and controlling inflammation through various signaling pathways.

 5. Anti-Inflammatory Activity: LL-37 reduces pro-inflammatory cytokines and promotes the production of anti-inflammatory cytokines, mitigating inflammatory responses.

 6. Cancer Prevention: Shows promise in inhibiting proliferation and suppressing tumor growth in various cancers, including colon and gastric cancers.

 7. Cardioprotective Effects: LL-37 aids in reducing cardiac hypertrophy, enhancing cardiac function, and inhibiting atherosclerosis progression.

 8. Lung Health: Improves outcomes in diseases like COPD by aiding in the clearance of respiratory pathogens and supporting lung health.

Research Applications

 • Antimicrobial: Effective against resistant infections.

 • Anti-Biofilm: Useful in disrupting established biofilms.

 • Wound Healing: Promotes faster healing of wounds.

 • Immunomodulation: Helps in enhancing immune function and modulating inflammatory responses.

 • Cancer Prevention and Bone Repair: Has potential roles in cancer prevention and bone health maintenance.

 • Cardioprotective: Supports cardiovascular health.

 • Lung Health: Contributes to respiratory system efficacy.

Product Use: THIS PRODUCT IS STRICTLY FOR SCIENTIFIC RESEARCH PURPOSES ONLY. It should only be used in laboratory settings. All product information on this website is provided solely for educational purposes. The law strictly prohibits introducing this product into the body of humans or animals. Only licensed professionals should handle this product. This product is not a drug, food, or cosmetic and should not be improperly classified or used as such.