AOD-9604 5mg

What is AOD-9604?

AOD-9604 is a modified peptide derived from the last 15 amino acids (176-191) of the human Growth Hormone (GH), known as GH Frag 176-191. This peptide is designed specifically for fat burning and medically assisted weight loss.

Mechanism of Action:

AOD-9604 functions through a unique mechanism independent of the Growth Hormone receptor. It triggers fat release predominantly from obese fat cells, mimicking the way natural GH regulates fat metabolism, but without affecting blood sugar levels or growth.

Benefits of AOD-9604:

Fat Reduction: It effectively reduces body fat and promotes the release of fat from obese cells, helping to decrease overall fat stores, particularly in the abdominal area.

Enhanced Lipolysis: Stimulates the breakdown of fat while inhibiting lipogenesis (the conversion of non-fatty foods into body fat).

No Impact on Appetite or Blood Sugar: Unlike some other peptides, AOD-9604 does not increase hunger or raise cortisol levels, and it has no adverse effects on blood sugar or insulin levels.

Regenerative Properties: When used in combination with peptide BPC 157, it supports cartilage repair and regeneration.

Safety Profile: AOD-9604 does not affect IGF-1 levels, making it a safer option without the risk of promoting glucose intolerance or diabetes. Additionally, it does not seem to trigger an immune response.

Comparison to Other Peptides:

CJC-1295: Known for increasing overall GH levels, CJC-1295 is another potent fat-loss peptide. However, it can lead to increased hunger and raised cortisol, making AOD-9604 a preferable option for those focused solely on fat loss.

Avoiding GHRP: Peptides like GHRP-6 and GHRP-2 may increase appetite and cortisol levels, which can counteract fat loss efforts.

Research Insights:

Studies across rodents, pigs, dogs, and humans have demonstrated AOD-9604’s effectiveness in reducing fat and preventing new fat accumulation, with a particular emphasis on abdominal fat reduction.

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Molecular Formula: C78H125N23O23S2

Molecular Weight: 1817.1 g/mol

PubChem CID: 16131447

Synonyms: SCHEMBL2881677, NS00121659

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Research Applications:

Metabolic Health

Weight Loss

Musculoskeletal Health

Fat-Burning Effects:

Fragment 176-191: Known as the “lipolytic fragment” of HGH, it exhibits fat-burning effects in rodent studies.

2001 Study: AOD9604 reduced body weight and fat in obese mice, increasing beta-3 adrenergic receptors. It had no effect on lean or beta(3)-AR knock-out mice. This suggests alternative pathways for lipolysis at normal weight levels.

Potential Treatment for Prediabetes and Type 2 Diabetes:

Hypoglycemic Effect: Fragment 176-191 effectively lowers blood sugar levels and increases plasma insulin. It also reduces insulin sensitivity.

Cartilage Regeneration:

2015 Study: AOD9604 improved cartilage regeneration in rabbits with osteoarthritis, showing combined benefits with HA injections. This suggests potential for human cartilage regeneration therapies.

Side Effects:

 AOD9604 Trials: No common HGH-related side effects (e.g., insulin resistance, hypertension). Reported adverse events included headaches, fatigue, and dizziness.

Fragment 176-191: Likely shares AOD9604's safety profile but lacks direct clinical data. Research suggests it does not cause common HGH-related side effects.

Safety Note:

Fragment 176-191 is not FDA-approved for human use. Caution is required, and it should be handled by qualified professionals.

Product Use: THIS PRODUCT IS STRICTLY FOR SCIENTIFIC RESEARCH PURPOSES ONLY. It should only be used in laboratory settings. All product information on this website is provided solely for educational purposes. The law strictly prohibits introducing this product into the body of humans or animals. Only licensed professionals should handle this product. This product is not a drug, food, or cosmetic and should not be improperly classified or used as such.