5-amino-1mq 5mg

5-Amino-1MQ is a powerful small molecule known for its capacity to inhibit the enzyme nicotinamide N-methyltransferase (NNMT). Predominantly active in adipose tissue, NNMT plays a crucial role in metabolism and energy balance. By blocking this enzyme, 5-Amino-1MQ facilitates a significant increase in nicotinamide adenine dinucleotide (NAD+), a vital cofactor in cellular metabolism. This elevation in NAD+ not only enhances metabolic rate but also activates the gene sirtuin-1 (SIRT1), often referred to as the "longevity gene."

SIRT1 activation has profound anti-aging effects and impacts various cellular functions across the body. It helps mitigate the risk of numerous conditions, including diabetes, obesity, metabolic syndrome, atherosclerosis, cardiovascular diseases, as well as kidney, liver, and neurodegenerative diseases, and cancer. Studies have demonstrated that decreasing NNMT activity can lead to a reduction in fat cell size and fat deposits.

Additionally, 5-Amino-1MQ mimics the effects of caloric restriction by switching cells into a sirtuin mode of operation, where mitochondria optimize energy expenditure. This not only burns fat and improves metabolism but also enhances endurance and cardiovascular function. Remarkably, research involving mice has shown a 7% reduction in body mass over just 10 days without any changes to diet, underscoring the compound’s effectiveness in promoting weight loss and improving overall metabolic health.

• Molecular Formula: C₁₀H₁₁N₂⁺
• Molecular Weight: 159.21 g/mol
• Synonyms:
• SCHEMBL6403148
• CHEMBL4116828
• AKOS025269993

    Applications:

• Weight loss
• Bodybuilding
• Metabolism (NNMT inhibitor)
• Cognitive function

5-Amino-1MQ Peptide Research

  5-Amino-1MQ powder is a high-purity, research-grade compound designed for lab use. It serves as a potent inhibitor of the NNMT enzyme, which is crucial in managing energy metabolism and fat storage. By          blocking NNMT, 5-Amino-1MQ can influence cell methylation and alter metabolic pathways related to obesity and type 2 diabetes.

 Targeting NNMT with 5-Amino 1MQ

  5-Amino 1MQ specifically targets and inhibits NNMT, an enzyme active mainly in fatty tissues and linked to obesity and type 2 diabetes. By inhibiting NNMT, 5-Amino 1MQ disrupts its role in metabolism and         energy balance, offering a unique opportunity to deeply study these processes.

 Weight Loss and Obesity Management

 Research has demonstrated that inhibiting NNMT with agents like 5-Amino-1MQ can reduce fat mass and improve insulin resistance. This is particularly relevant for obesity studies, as NNMT levels are typically   higher in the fat tissue of obese individuals. Therefore, blocking NNMT with 5-Amino-1MQ might be a new method for tackling weight loss.

 Metabolic Regulation

 5-Amino-1MQ has been linked to beneficial changes in metabolism, such as increased insulin sensitivity and modified lipid metabolism. These findings are supported by metabolomic studies that have identified   specific lipid compounds and amino acid analogues that respond to weight loss interventions.

 NNMT Inhibition and Microbiome Changes

 Studies suggest that inhibiting NNMT can lead to a distinct microbiome profile, important because the gut microbiota plays a role in the development of metabolic diseases. Experiments on mice with diet-induced  obesity showed that reducing calorie intake combined with NNMT inhibition results in a unique microbiome composition, suggesting potential uses for 5-Amino-1MQ in microbiota-related metabolic research.

 Enhanced Understanding of Metabolism

 Using 5-Amino-1MQ in research helps provide deeper insights into metabolic pathways involved in obesity and related conditions, aiding in the development of targeted therapies and personalized medicine for   metabolic disorders.

Product Use: 

THIS PRODUCT IS STRICTLY FOR SCIENTIFIC RESEARCH PURPOSES ONLY. It should only be used in laboratory settings. All product information on this website is provided solely for educational purposes. The law strictly prohibits introducing this product into the body of humans or animals. Only licensed professionals should handle this product. This product is not a drug, food, or cosmetic and should not be improperly classified or used as such.