Kisspeptin-10 10mg

Kisspeptin-10 is a synthetic peptide that mimics the naturally occurring kisspeptin protein, which plays a crucial role in reproductive health and hormone regulation. This peptide activates GnRH neurons, influencing the release of two key reproductive hormones: Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). Kisspeptin-10 has been shown to increase testosterone, stimulate sexual arousal, improve mood, and support fertility in both men and women. Additionally, it may help prevent the spread of cancer, regulate kidney function, and promote new blood vessel growth. Kisspeptin-10 is considered a promising treatment for reproductive and sexual health disorders.

What is Kisspeptin-10?

Kisspeptin-10 is a significant peptide that regulates the human reproductive system. It plays a crucial role in stimulating the release of gonadotropin in both men and women, increasing testosterone levels and the frequency of luteinizing hormone (LH) pulses in men. In addition to its reproductive function, Kisspeptin-10 also impacts metabolism and appetite control by influencing neurotransmitters in the brain. Moreover, it may affect collagen content in the heart.

Kisspeptin-10 and Testosterone Levels

Research shows that Kisspeptin-10 significantly impacts testosterone levels in men:

A 2011 study revealed that bolus injections of Kisspeptin-10 strongly stimulate LH secretion in men, and continuous infusion increases testosterone levels, LH pulse frequency, and pulse size [R].

In men with type 2 diabetes and central hypogonadism, Kisspeptin-10 was found to enhance endogenous testosterone secretion [R].

Another study demonstrated that Kisspeptin-10 stimulates gonadotropin release in men but not in women [R].

Kisspeptin-10 and Reproductive Health

Kisspeptin-10 stimulates the release of gonadotropin, a hormone essential for reproductive health in men. In women, its effects are more nuanced: it stimulates gonadotropin during the pre-ovulatory phase of the menstrual cycle, but not during other phases. This indicates sexual dimorphism in the response to Kisspeptin-10 [R].

Kisspeptin-10 may also serve as a potential therapeutic agent for treating reproductive disorders. For instance, a variant of the peptide, Kisspeptin-54, has been successfully used to induce oocyte maturation in women undergoing in vitro fertilization (IVF) treatment [R].

Kisspeptin-10 and Sexual Arousal

A 2023 study found that Kisspeptin-10 improves sexual mood and promotes penile tumescence in men with hypoactive sexual desire disorder (HSDD) [R].

In women, Kisspeptin-10 modulated brain activity related to sexual perception, helping to reduce sexual aversion [R].

Kisspeptin-10 and Metabolism

A 2018 study discovered that Kisspeptin-10 could influence the expression of neuropeptide Y (NPY), a key regulator of appetite, as well as serotonin and dopamine levels, both of which play a role in appetite control [R].

Additionally, a 2020 study showed that Kisspeptin-10 affects the brain's response to visual food stimuli, potentially influencing appetite and eating behavior [R].

Kisspeptin-10 and Cancer Research

Research from 2018 demonstrated that Kisspeptin signaling can suppress cancer cell metastasis by inhibiting their proliferation, migration, and invasion [R].

In studies on breast cancer cell lines, Kisspeptin-10 was shown to inhibit cancer cell migration by regulating the epithelial-mesenchymal transition process [R].

Kisspeptin-10 and Heart Disease

A 2017 study found that Kisspeptin-10 may affect serum metabolism and cardiac muscle, indicating potential for its use in cardiovascular disease therapy [R].

A 2023 study revealed that Kisspeptin-10 increases collagen content in the myocardium, which could impact the progression of heart disease

Molecular Formula:
C₆₃H₈₃N₁₇O₁₄

Molecular Weight:
1302.4 g/mol

PubChem CID:
25240297

Synonyms:

• Kisspeptin-10
• 374675-21-5
• Kisspeptin-10 (human)
• Metastin (45-54)
• KP-10

Research Applications:

• Testosterone
• Reproductive Health
• Sexual Arousal
• Metabolism
• Appetite Control
• Cancer Research
• Heart Disease

Product Use: THIS PRODUCT IS STRICTLY FOR SCIENTIFIC RESEARCH PURPOSES ONLY. It should only be used in laboratory settings. All product information on this website is provided solely for educational purposes. The law strictly prohibits introducing this product into the body of humans or animals. Only licensed professionals should handle this product. This product is not a drug, food, or cosmetic and should not be improperly classified or used as such.